Mozobil

Generic Name: plerixafor (Subcutaneous route)

pler-IX-a-fore

Commonly used brand name(s)

In the U.S.

• Mozobil

Available Dosage Forms:

• Solution

Therapeutic Class: Hematopoietic

Uses For Mozobil

Plerixafor is used to treat non-Hodgkin's lymphoma (NHL) and multiple myeloma (MM). It is used together with granulocyte-colony stimulating factor or G-CSF (e.g., filgrastim, pegfilgrastim) to mobilize hematopoietic stem cells (HSC) for collection and transplantation.

This medicine is available only with your doctor's prescription.

Before Using Mozobil

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of plerixafor in the pediatric population.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of plerixafor in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require an adjustment of dose in patients receiving plerixafor.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	D	Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Bone marrow cancer or other bone marrow problems (e.g., leukemia) or


• Enlarged spleen or


• Leukocytosis (high white blood cell count) or


• Thrombocytopenia (low blood platelet count)—Use with caution. May make these conditions worse.

• Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of Mozobil

A nurse or other trained health professional may give you this medicine. This medicine is given as a shot under your skin.

Precautions While Using Mozobil

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects.

Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If a pregnancy occurs while you are using this medicine, tell your doctor right away. Do not breastfeed while you are using this medicine.

Check with your doctor right away if you are having a pain in the upper left part of your abdomen or at the tip of the left shoulder. This could be a symptom of a serious side effect with the spleen.

Tell your doctor right away if you have slow heartbeat; severe, unusual tiredness or weakness; cold sweats; confusion; or dizziness, faintness, or lightheadedness when getting up from a lying or sitting position after you get the injection.

If you develop a skin rash, hives, swelling around the eyes, shortness of breath, or any allergic reaction to this medicine, stop taking the medicine and check with your doctor as soon as possible.

This medicine may cause diarrhea, nausea, vomiting, or stomach pain in some patients. Ask your doctor or nurse about other ways to control these side effects.

Mozobil Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Bleeding gums


• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings


• collection of blood under skin


• coughing up blood


• deep, dark purple bruise


• difficulty in breathing or swallowing


• dizziness


• feeling of heat


• flushing, redness of the skin


• hard lump


• headache


• hives or welts


• increased menstrual flow or vaginal bleeding


• irritation


• itching skin


• nosebleeds


• pain


• paralysis


• prolonged bleeding from cuts


• red or black, tarry stools


• red or dark brown urine


• redness of the skin


• shortness of breath


• skin rash


• swelling


• unusually warm skin

Rare

• Chills


• cold sweats


• confusion


• dizziness, faintness, or lightheadedness when getting up from a lying or sitting position


• fainting


• fast heartbeat


• swelling around the eyes


• tightness in the chest


• weakness


• wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Bloated


• diarrhea


• difficulty in moving


• excess air or gas in stomach or intestines


• full feeling


• muscle pain or stiffness


• nausea


• pain in the joints


• passing gas


• sleeplessness


• trouble sleeping


• unable to sleep


• unusual tiredness or weakness


• vomiting

Less common

• Acid or sour stomach


• belching


• difficulty having a bowel movement (stool)


• dry mouth


• general feeling of discomfort or illness


• heartburn


• increased sweating


• indigestion


• muscle or bone pain


• pressure in the stomach


• stomach discomfort, upset, or pain


• swelling of abdominal or stomach area

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Mozobil side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Mozobil resources

• Mozobil Side Effects (in more detail)
• Mozobil Use in Pregnancy & Breastfeeding
• Mozobil Support Group
• 0 Reviews for Mozobil - Add your own review/rating

• Mozobil Prescribing Information (FDA)


• Mozobil MedFacts Consumer Leaflet (Wolters Kluwer)


• Mozobil Consumer Overview


• Plerixafor Professional Patient Advice (Wolters Kluwer)

Compare Mozobil with other medications

• Multiple Myeloma
• Non-Hodgkin's Lymphoma

Midazolam

Pronunciation: meh-DAZE-oh-lam
Generic Name: Midazolam
Brand Name: Generic only. No brands available.

Midazolam may cause severe breathing problems (eg, respiratory depression, respiratory arrest), especially when used for sedation in noncritical care settings. Respiratory depression and respiratory arrest could result in brain damage or death if not treated properly. Midazolam should only be used under appropriate close medical supervision.

Do not give Midazolam by rapid intravenous (IV) injection to newborn infants (neonates). Severe low blood pressure and seizures have occurred in neonates when given Midazolam by rapid IV injection, especially when given at the same time as fentanyl.

Midazolam is used for:

Reducing anxiety or producing drowsiness or anesthesia before certain medical procedures or surgery. It may also be given continuously to maintain sedation or anesthesia in certain patients. It may also be used for other conditions as determined by your doctor.

Midazolam is a benzodiazepine. It works in the central nervous system (brain) to cause sleepiness, muscle relaxation, and short-term memory loss, and to reduce anxiety.

Do NOT use Midazolam if:

• you are allergic to any ingredient in Midazolam


• you have acute narrow-angle glaucoma, severe mental problems (eg, psychosis), or severe liver disease


• you have alcohol intoxication with abnormal vital signs


• you are taking delavirdine, efavirenz, an HIV protease inhibitor (eg, ritonavir), or sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

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Treatments for depression are getting better everyday and there are things you can start doing right away.

Before using Midazolam:

Some medical conditions may interact with Midazolam. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have breathing problems (eg, COPD); open-angle glaucoma; heart, liver, or kidney problems; the blood disease porphyria; severe depression; or a history of drug abuse or dependence; or if you have used alcohol recently

Some MEDICINES MAY INTERACT with Midazolam. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Carbamazepine, rifampin, or St. John's wort because the effectiveness of Midazolam may be decreased


• Azole antifungals (eg, itraconazole), barbiturates (eg, phenobarbital), clozapine, delavirdine, diltiazem, disulfiram, efavirenz, grapefruit juice, HIV protease inhibitors (eg, ritonavir), ketolides (eg, telithromycin), macrolides (eg, erythromycin), narcotic pain medicines (eg, codeine), nefazodone, omeprazole, sodium oxybate (GHB), valproic acid, or verapamil and its derivatives because serious side effects, such as low blood pressure, breathing problems, and excessive sedation, may occur


• Hydantoins because side effects may be increased by Midazolam

This may not be a complete list of all interactions that may occur. Ask your health care provider if Midazolam may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Midazolam:

Use Midazolam as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Midazolam is usually administered as an injection at your doctor's office, clinic, or hospital. Ask your doctor or pharmacist any questions that you may have about Midazolam.


• If Midazolam contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.


• Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.


• If you miss a dose of Midazolam, contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Midazolam.

Important safety information:

• Midazolam may cause drowsiness or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until the effects of Midazolam have disappeared or until the day after you receive Midazolam, whichever is longer. Using Midazolam alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.


• Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while using Midazolam. Midazolam will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.


• Midazolam can cause partial or complete memory loss for several hours.


• Use Midazolam with caution in the ELDERLY because they may be more sensitive to its effects.


• Caution is advised when using Midazolam in CHILDREN because they may be more sensitive to its effects.


• PREGNANCY and BREAST-FEEDING: Midazolam has been shown to cause harm to the fetus. If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Midazolam during pregnancy. Midazolam is excreted in breast milk. If you are or will be breast-feeding while you are using Midazolam, check with your doctor or pharmacist to discuss the risks to your baby.

When used for long periods of time or at high doses, some people develop a need to continue taking Midazolam. This is known as DEPENDENCE or addiction.

If you use Midazolam for long periods of time or at high doses and suddenly stop taking Midazolam, you may experience WITHDRAWAL symptoms including fast heartbeat, hallucinations, muscle cramps, seizures, stomach cramps, sweating, tremor, and vomiting.

Possible side effects of Midazolam:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; changes in blood pressure, breathing, and heartbeats; coughing; dizziness; drowsiness; dry mouth; headache; hiccups; low blood pressure (children); nausea; pain during injection; pain, redness, or tenderness at the injection site; short-term memory loss; slurred speech; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; chest pain; combativeness; irregular breathing patterns; pain, swelling, or redness at the injection site; slow or difficult breathing; unusual or involuntary muscle movements or muscle tremor.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Midazolam side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include clumsiness; confusion; deep sleep; loss of consciousness; sleepiness; slow reflexes.

Proper storage of Midazolam:

Midazolam is usually handled and stored by a health care provider. If you are using Midazolam at home, store Midazolam as directed by your pharmacist or health care provider. Store away from heat, moisture, and light. Keep Midazolam out of the reach of children and away from pets.

General information:

• If you have any questions about Midazolam, please talk with your doctor, pharmacist, or other health care provider.


• Midazolam is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Midazolam. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Midazolam resources

• Midazolam Side Effects (in more detail)
• Midazolam Use in Pregnancy & Breastfeeding
• Midazolam Drug Interactions
• Midazolam Support Group
• 6 Reviews for Midazolam - Add your own review/rating

• midazolam Advanced Consumer (Micromedex) - Includes Dosage Information


• Midazolam Hydrochloride Monograph (AHFS DI)

Compare Midazolam with other medications

• ICU Agitation
• Light Anesthesia
• Light Sedation

Lacticare-HC

Generic Name: hydrocortisone (Topical application route)

hye-droe-KOR-ti-sone

Commonly used brand name(s)

In the U.S.

• Ala-Cort


• Ala-Scalp HP


• Anusol HC


• Aquanil HC


• Beta HC


• Caldecort


• Cetacort


• Corta-Cap


• Cortagel Extra Strength


• Cortaid


• CortAlo With Aloe


• Corticaine


• Corticool Maximum Strength


• Cortizone-10


• Cortizone-5


• Cotacort


• Delacort


• Dermarest


• Dermtex-HC


• Foille Cort


• Gly-Cort


• Hydrozone Plus


• Hytone


• Instacort-10


• Ivy Soothe


• IvyStat


• Keratol HC


• Kericort 10


• Lacticare-HC


• Locoid


• Locoid Lipocream


• Medi-Cortisone Maximum Strength


• Microcort


• Mycin Scalp


• Neutrogena T/Scalp


• NuCort


• Nupercainal HC


• Nutracort


• Pandel


• Pediaderm HC Kit


• Preparation H Hydrocortisone


• Proctocream-HC


• Recort Plus


• Sarnol-HC Maximum Strength


• Scalacort


• Scalpcort


• Summer's Eve Specialcare


• Texacort


• Therasoft Anti-Itch & Dermatitis


• U-Cort


• Westcort

In Canada

• Barriere-Hc


• Cortate


• Cort-Eze


• Cortoderm Mild Ointment


• Cortoderm Regular Ointment


• Emo-Cort


• Emo-Cort Scalp Solution


• Hydrocortisone Cream


• Novo-Hydrocort


• Novo-Hydrocort Cream


• Prevex Hc


• Sarna Hc

Available Dosage Forms:

• Solution


• Cream


• Spray


• Lotion


• Ointment


• Pad


• Liquid


• Gel/Jelly


• Kit


• Foam


• Stick


• Paste

Therapeutic Class: Corticosteroid, Weak

Pharmacologic Class: Adrenal Glucocorticoid

Uses For Lacticare-HC

Hydrocortisone topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. This medicine is a corticosteroid (cortisone-like medicine or steroid).

This medicine is available both over-the-counter (OTC) and with your doctor's prescription.

Before Using Lacticare-HC

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of hydrocortisone topical in the pediatric population. However, because of this medicine's toxicity, it should be used with caution. Children may absorb large amounts through the skin, which can cause serious side effects. If your child is using this medicine, follow your doctor's instructions very carefully.

Geriatric

No information is available on the relationship of age to the effects of hydrocortisone topical in geriatric patients.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Cushing's syndrome (adrenal gland disorder) or


• Diabetes or


• Hyperglycemia (high blood sugar) or


• Intracranial hypertension (increased pressure in the head)—Use with caution. May make these conditions worse.

• Infection of the skin at or near the place of application or


• Large sores, broken skin, or severe skin injury at the place of application—The chance of side effects may be increased.

Proper Use of hydrocortisone

This section provides information on the proper use of a number of products that contain hydrocortisone. It may not be specific to Lacticare-HC. Please read with care.

It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.

This medicine is for use on the skin only. Do not get it in your eyes. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

This medicine should only be used for skin conditions that your doctor is treating. Check with your doctor before using it for other conditions, especially if you think that a skin infection may be present. This medicine should not be used to treat certain kinds of skin infections or conditions, such as severe burns.

To use:

• Wash your hands with soap and water before and after using this medicine.


• Apply a thin layer of this medicine to the affected area of the skin. Rub it in gently.


• With the lotion, shake it well before using.


• Do not bandage or otherwise wrap the skin being treated unless directed to do so by your doctor.


• If the medicine is applied to the diaper area of an infant, do not use tight-fitting diapers or plastic pants unless directed to do so by your doctor.


• If your doctor ordered an occlusive dressing or airtight covering to be applied over the medicine, make sure you know how to apply it. Occlusive dressings increase the amount of medicine absorbed through your skin, so use them only as directed. If you have any questions about this, check with your doctor.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For redness, itching, and swelling of the skin:
  
  • For topical dosage form (cream):
    
    • Adults—Apply to the affected area of the skin two or three times per day.
    
    
    • Children—Apply to the affected area of the skin two or three times per day.
    
    
  
  
  • For topical dosage form (lotion):
    
    • Adults—Apply to the affected area of the skin two to four times per day.
    
    
    • Children—Apply to the affected area of the skin two to four times per day.
    
    
  
  
  • For topical dosage form (ointment):
    
    • Adults—Apply to the affected area of the skin three or four times per day.
    
    
    • Children—Apply to the affected area of the skin three or four times per day.
    
    
  
  
  • For topical dosage form (solution):
    
    • Adults—Apply to the affected area of the skin three or four times per day.
    
    
    • Children—Apply to the affected area of the skin three or four times per day.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Lacticare-HC

It is very important that your doctor check your or your child's progress at regular visits for any unwanted effects that may be caused by this medicine.

If your or your child's symptoms do not improve within a few days, or if they become worse, check with your doctor.

Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. The risk is greater for children and patients who use large amounts for a long time. Talk to your doctor right away if you or your child have more than one of these symptoms while you are using this medicine: blurred vision; dizziness or fainting; a fast, irregular, or pounding heartbeat; increased thirst or urination; irritability; or unusual tiredness or weakness.

Stop using this medicine and check with your doctor right away if you or your child have a skin rash, burning, stinging, swelling, or irritation on the skin.

Do not use cosmetics or other skin care products on the treated areas.

Lacticare-HC Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

• Blistering, burning, crusting, dryness, or flaking of the skin


• irritation


• itching, scaling, severe redness, soreness, or swelling of the skin


• redness and scaling around the mouth


• thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (e.g. between the fingers)


• thinning, weakness, or wasting away of the skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

• Acne or pimples


• burning and itching of the skin with pinhead-sized red blisters


• burning, itching, and pain in hairy areas, or pus at the root of the hair


• increased hair growth on the forehead, back, arms, and legs


• lightening of normal skin color


• lightening of treated areas of dark skin


• reddish purple lines on the arms, face, legs, trunk, or groin


• softening of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Lacticare-HC side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Lacticare-HC resources

• Lacticare-HC Side Effects (in more detail)
• Lacticare-HC Use in Pregnancy & Breastfeeding
• Lacticare-HC Drug Interactions
• Lacticare-HC Support Group
• 0 Reviews for Lacticare-HC - Add your own review/rating

• Ala-Cort Concise Consumer Information (Cerner Multum)


• Anucort-HC cream, ointment, suppository Concise Consumer Information (Cerner Multum)


• Anusol-HC Cream MedFacts Consumer Leaflet (Wolters Kluwer)


• Carmol HC Prescribing Information (FDA)


• Carmol HC MedFacts Consumer Leaflet (Wolters Kluwer)


• Carmol HC Concise Consumer Information (Cerner Multum)


• Cortizone-10 Cream MedFacts Consumer Leaflet (Wolters Kluwer)


• Hydrocortisone Acetate Monograph (AHFS DI)


• Hydrocortisone with Aloe Cream MedFacts Consumer Leaflet (Wolters Kluwer)


• Hytone Prescribing Information (FDA)


• Instacort Gel MedFacts Consumer Leaflet (Wolters Kluwer)


• Locoid Cream MedFacts Consumer Leaflet (Wolters Kluwer)


• Locoid Lipocream Prescribing Information (FDA)


• Locoid Lotion Prescribing Information (FDA)


• Nutracort Lotion MedFacts Consumer Leaflet (Wolters Kluwer)


• Nutracort Concise Consumer Information (Cerner Multum)


• Pandel Prescribing Information (FDA)


• Pediaderm HC Lotion MedFacts Consumer Leaflet (Wolters Kluwer)


• ProctoCream-HC Cream MedFacts Consumer Leaflet (Wolters Kluwer)


• Proctocort Prescribing Information (FDA)


• Texacort Prescribing Information (FDA)


• U-cort Prescribing Information (FDA)


• Westcort Prescribing Information (FDA)

Compare Lacticare-HC with other medications

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• Proctitis
• Pruritus
• Psoriasis
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• Skin Rash
• Ulcerative Colitis, Active

Mafenide Topical

MAF-en-ide

Commonly used brand name(s)

In the U.S.

• Sulfamylon

Available Dosage Forms:

• Powder for Suspension


• Powder for Solution


• Cream

Therapeutic Class: Antibacterial

Chemical Class: Sulfonamide

Uses For mafenide

Mafenide, a sulfa medicine, is used to prevent and treat bacterial or fungus infections. It works by preventing growth of the fungus or bacteria.

Mafenide cream is applied to the skin and/or burned area(s) to prevent and treat bacterial or fungus infections that may occur in burns.

Other medicines are used along with mafenide for burns. Patients with severe burns or burns over a large area of the body must be treated in a hospital.

mafenide is available only with your doctor's prescription.

Before Using mafenide

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For mafenide, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to mafenide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Use of mafenide is not recommended in premature or newborn infants up to 2 months of age. Sulfa medicines may cause liver problems in these infants.

Geriatric

Many medicines have not been tested in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of mafenide in the elderly with use in other age groups.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of mafenide. Make sure you tell your doctor if you have any other medical problems, especially:

• Blood problems—Use of mafenide may make the condition worse.

• Glucose-6-phosphate dehydrogenase deficiency (lack of G6PD enzyme)—Use of mafenide in persons with this condition may result in hemolytic anemia.

• Kidney problems or


• Lung problems or


• Metabolic acidosis—Use of mafenide in persons with any of these conditions may increase the risk of a side effect called metabolic acidosis.

Proper Use of mafenide

To use:

• Before applying mafenide, cleanse the affected area(s). Remove dead or burned skin and other debris.


• Wear a sterile glove to apply mafenide. For the topical creak, apply a thin layer (about 1/16 inch) of mafenide to the affected area(s). For the topical solution, the solution is applied to the dressing covering the affected area(s). Keep the affected area(s) covered with the medicine at all times.


• If mafenide is rubbed off the affected area(s) by moving around or if it is washed off during bathing, showering, or the use of a whirlpool bath, reapply the medicine.


• After mafenide has been applied, the treated area(s) may be covered with a dressing or left uncovered as desired.

To help clear up your skin and/or burn infection completely, keep using mafenide for the full time of treatment. You should keep using mafenide until the burn area has healed or is ready for skin grafting. Do not miss any doses.

Dosing

The dose of mafenide will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of mafenide. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For topical dosage form (cream):
  
  • For bacterial or fungus infection:
    
    • Adults and children 2 months of age and over—Use one or two times a day.
    
    
    • Infants and children up to 2 months of age—Use is not recommended.
    
    
  
  


• For topical dosage form (solution):
  
  • For bacterial or fungus infection:
    
    • Adults and children 3 months of age and over—Use every 4 to 8 hours each day as needed to keep the dressing wet.
    
    
    • Infants and children up to 3 months of age—Use is not recommended.
    
    
  
  

Missed Dose

If you miss a dose of mafenide, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using mafenide

It is important that your doctor check your progress at regular visits.

If your skin infection or burn does not improve within a few days or if your more serious burns or burns over larger areas do not improve within a few weeks, or if they become worse, check with your doctor.

mafenide Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

• Itching


• skin rash or redness


• swelling of face or skin


• wheezing or troubled breathing

Rare

• Bleeding or oozing of skin


• drowsiness


• fast, deep breathing


• nausea

Incidence unknown

• Black, tarry stools


• chest pain


• chills


• cough or hoarseness


• dark urine


• dizziness


• fever


• fluid-filled skin blisters


• light-colored stools


• lower back or side pain


• numbness to feet, hands and around mouth


• painful or difficult urination


• rapid shallow breathing


• sensitivity to the sun


• shortness of breath


• skin thinness


• sore throat


• sores, ulcers, or white spots on lips or in mouth


• swollen glands


• unusual bleeding or bruising


• unusual tiredness or weakness


• yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Pain or burning feeling on treated area(s)

Incidence unknown

• Blisters


• flushing


• raised red swellings on the skin, lips, tongue, or in the throat


• redness of skin


• skin rash


• softening of the skin


• swelling


• unusually warm skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: mafenide Topical side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More mafenide Topical resources

• Mafenide Topical Side Effects (in more detail)
• Mafenide Topical Use in Pregnancy & Breastfeeding
• Mafenide Topical Support Group
• 0 Reviews for Mafenide Topical - Add your own review/rating

• mafenide topical Concise Consumer Information (Cerner Multum)


• Sulfamylon Prescribing Information (FDA)


• Sulfamylon Monograph (AHFS DI)


• Sulfamylon Cream MedFacts Consumer Leaflet (Wolters Kluwer)

Compare mafenide Topical with other medications

• Burns, External

Lamisil AT Cream

Pronunciation: TER-bin-a-feen
Generic Name: Terbinafine
Brand Name: Lamisil AT

Lamisil AT Cream is used for:

Relieving itching, burning, cracking, and scaling associated with jock itch, athlete's foot, ringworm, and other fungal infections of the skin.

Lamisil AT Cream is topical antifungal agent. It works by killing sensitive fungi.

Do NOT use Lamisil AT Cream if:

• you are allergic to any ingredient in Lamisil AT Cream

Contact your doctor or health care provider right away if any of these apply to you.

Before using Lamisil AT Cream:

Some medical conditions may interact with Lamisil AT Cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have kidney problems

Some MEDICINES MAY INTERACT with Lamisil AT Cream. Because little, if any, of Lamisil AT Cream is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Lamisil AT Cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Lamisil AT Cream:

Use Lamisil AT Cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Wash the affected area with soap and water. Be sure the area is completely dry before applying Lamisil AT Cream.


• Apply a thin layer of medicine and rub in gently as directed by your doctor or the package labeling.


• If you are using Lamisil AT Cream for athlete's foot, make sure you apply the medicine to the spaces between the toes. Wear well-fitting, ventilated shoes. Change shoes and socks at least once a day.


• Wash your hands immediately after using Lamisil AT Cream unless your hands are part of the treated area.


• To clear up your infection completely, use Lamisil AT Cream for the full course of treatment. Keep using it even if you notice improvement in a few days.


• If you miss a dose of Lamisil AT Cream, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Lamisil AT Cream.

Important safety information:

• Lamisil AT Cream is for external use only. Do not get it in your eyes, nose, or mouth. If you get it in any of these areas, rinse right away with cool water.


• Do not use Lamisil AT Cream on the nails or scalp. Do not use it for vaginal yeast infections.


• Do not use more than the recommended dose or use for longer than prescribed without checking with your doctor.


• Lamisil AT Cream should not be used in CHILDREN younger than 12 years old without first checking with your child's doctor; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Lamisil AT Cream while you are pregnant. It is not known if Lamisil AT Cream is found in breast milk after topical use. If you are or will be breast-feeding while you use Lamisil AT Cream, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Lamisil AT Cream:

All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); new or worsening skin irritation.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Lamisil AT side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Lamisil AT Cream:

Store Lamisil AT Cream between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Lamisil AT Cream out of the reach of children and away from pets.

General information:

• If you have any questions about Lamisil AT Cream, please talk with your doctor, pharmacist, or other health care provider.


• Lamisil AT Cream is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Lamisil AT Cream. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Lamisil AT resources

• Lamisil AT Side Effects (in more detail)
• Lamisil AT Use in Pregnancy & Breastfeeding
• Lamisil AT Support Group
• 4 Reviews for Lamisil AT - Add your own review/rating

Compare Lamisil AT with other medications

• Tinea Corporis
• Tinea Cruris
• Tinea Pedis

Laxative Rectal

Class Name: laxative (Rectal route)

Commonly used brand name(s)

In the U.S.

• Biscolax


• Colace


• Dulcolax


• Dulcolax Bowel Cleansing Kit


• Enemeez Mini Enema


• Enemeez Plus Mini Enema


• Fleet Babylax


• Fleet Bisacodyl


• Fleet Glycerin


• Fleet Mineral Oil


• Sani-Supp


• The Magic Bullet

In Canada

• Apo-Bisacodyl


• Bisacodyl Adult


• Bisacodyl Children


• Bisacolax


• Dulcolax Adult's


• Dulcolax Children's


• Evac-Q-Kwik


• Fleet Enema Mineral Oil


• Glycerin Adult


• Glycerin Infants And Children


• Glycerin Suppositories Adult


• Glycerin Suppositories Infants And Children

Available Dosage Forms:

• Enema


• Suppository

Uses For This Medicine

Rectal laxatives are used as enemas or suppositories to produce bowel movements in a short time.

There are several different types of rectal laxatives and they work in different ways. Since directions for use are different for each type, it is important to know which one you are taking. The different types of rectal laxatives include:

• Carbon dioxide-releasing


• Carbon dioxide-releasing laxatives (e.g., potassium bitartrate and sodium bicarbonate) are suppositories that encourage bowel movements by forming carbon dioxide, a gas. This gas pushes against the intestinal wall, causing contractions that move along the stool mass.

• Hyperosmotic


• Hyperosmotic laxatives (e.g., glycerin; sodium phosphates) draw water into the bowel from surrounding body tissues. This provides a soft stool mass and increased bowel action.

• Lubricant


• Mineral oil coats the bowel and the stool mass with a waterproof film. This keeps moisture in the stool. The stool remains soft and its passage is made easier.

• Stimulants


• Stimulant laxatives (e.g., bisacodyl; senna), also known as contact laxatives, act on the intestinal wall. They increase the muscle contractions that move along the stool mass.

• Stool softeners (emollients)


• Stool softeners (emollient laxatives—e.g., docusate) encourage bowel movements by helping liquids mix into the stool and prevent dry, hard stool masses. This type of laxative has been said not to cause a bowel movement but instead allows the patient to have a bowel movement without straining.

Rectal laxatives may provide relief in a number of situations such as:

• before giving birth.


• for a few days after giving birth.


• preparation for examination or surgery.


• to aid in developing normal bowel function following a period of poor eating habits or a lack of physical exercise (glycerin suppositories only).


• following surgery when straining should be avoided.


• constipation caused by other medicines.

Some of these laxatives are available only with your doctor's prescription. Others are available without a prescription; however, your doctor may have special instructions for the proper use and dose for your medical condition.

Before Using This Medicine

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Laxatives should not be given to young children (up to 6 years of age) unless prescribed by their doctor. Since children cannot usually describe their symptoms very well, they should be checked by a doctor before being given a laxative. The child may have a condition that needs other treatment. If so, laxatives will not help and may even cause unwanted effects or make the condition worse.

Also, weakness, increased sweating, and convulsions (seizures) may be especially likely to occur in children receiving enemas or rectal solutions, since they may be more sensitive than adults to their effects.

Geriatric

Weakness, increased sweating, and convulsions (seizures) may be especially likely to occur in elderly patients, since they may be more sensitive than younger adults to the effects of rectal laxatives.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of medicines in this class. Make sure you tell your doctor if you have any other medical problems, especially:

• Appendicitis (or signs of) or


• Rectal bleeding of unknown cause—These conditions need immediate attention by a doctor.

• Intestinal blockage—The use of laxatives may create other problems if this condition is present.

Proper Use of This Medicine

For safe and effective use of laxatives:

• Follow your doctor's orders if this laxative was prescribed.


• Follow the manufacturer's package directions if you are treating yourself.

For patients using the enema or rectal solution form of this medicine:

• This medicine usually comes with patient directions. Read them carefully before using this medicine.


• Lubricate anus with petroleum jelly before inserting the enema applicator.


• Gently insert the rectal tip of the enema applicator to prevent damage to the rectal wall.


• Results often may be obtained with:
  
  • bisacodyl enema in 15 minutes to 1 hour.
  
  
  • docusate enema in 2 to 15 minutes.
  
  
  • glycerin enema in 15 minutes to 1 hour.
  
  
  • mineral oil enema in 2 to 15 minutes.
  
  
  • senna enema in 30 minutes, but may not occur for some individuals for up to 2 hours.
  
  
  • sodium phosphates enema in 2 to 5 minutes.
  
  

For patients using the suppository form of this medicine:

• If the suppository is too soft to insert, chill the suppository in the refrigerator for 30 minutes or run cold water over it, before removing the foil wrapper.


• To insert suppository: First remove the foil wrapper and moisten the suppository with cold water. Lie down on your side and use your finger to push the suppository well up into the rectum.


• Results often may be obtained with:
  
  • bisacodyl suppositories in 15 minutes to 1 hour.
  
  
  • carbon dioxide–releasing suppositories in 5 to 30 minutes.
  
  
  • glycerin suppositories in 15 minutes to 1 hour.
  
  
  • senna suppositories in 30 minutes, but may not occur for some individuals for up to 2 hours.
  
  

There are a large number of laxative products on the market. The dose of laxatives will be different for different products. The amount of enema or the number of suppositories that you use depends on the strength of the medicine. Follow your doctor's orders if this medicine was prescribed, or follow the directions on the box if you are buying this medicine without a prescription.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using This Medicine

Do not use any type of laxative:

• if you have signs of appendicitis or inflamed bowel (such as stomach or lower abdominal pain, cramping, bloating, soreness, nausea, or vomiting). Instead, check with your doctor as soon as possible.


• more often than your doctor prescribed. This is true even when you have had no results from the laxative


• if you do not need it, as for the common cold, "to clean out your system," or as a "tonic to make you feel better."


• if you miss a bowel movement for a day or two

If you notice a sudden change in bowel habits or function that lasts longer than 2 weeks, or keeps returning off and on, check with your doctor before using a laxative. This will allow the cause of your problem to be determined before it becomes more serious.

The "laxative habit"—Laxative products are overused by many people. Such a practice often leads to dependence on the laxative action to produce a bowel movement. In severe cases, overuse of some laxatives has caused damage to the nerves, muscles, and tissues of the intestines and bowel. If you have any questions about the use of laxatives, check with your health care professional.

For patients using the enema or rectal solution form of this medicine:

• Check with your doctor if you notice rectal bleeding, blistering, pain, burning, itching, or other sign of irritation not present before you started using this medicine

For patients using the suppository form of this medicine:

• Do not lubricate the suppository with mineral oil or petroleum jelly before inserting into the rectum. To do so may affect the way the suppository works. Moisten only with water.

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common

• Rectal bleeding, blistering, burning, itching, or pain (with enemas only)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Skin irritation surrounding rectal area

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products.

Mucomyst Solution

Pronunciation: a-SEET-il-SIS-teen
Generic Name: Acetylcysteine
Brand Name: Generic only. No brands available.

Mucomyst Solution is used for:

Treatment of abnormal, sticky, or thick mucus secretions in various lung problems (eg, chronic emphysema, bronchitis, asthmatic bronchitis, pneumonia, during anesthesia, following surgery or various lung tests).

Mucomyst Solution is a mucolytic. It works by thinning out mucus secretions, making them easier to move through the lungs.

Do NOT use Mucomyst Solution if:

• you are allergic to any ingredient in Mucomyst Solution

Contact your doctor or health care provider right away if any of these apply to you.

Before using Mucomyst Solution:

Some medical conditions may interact with Mucomyst Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Mucomyst Solution. However, no specific interactions with Mucomyst Solution are known at this time.

Ask your health care provider if Mucomyst Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Mucomyst Solution:

Use Mucomyst Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Mucomyst Solution is inhaled into the lungs using a nebulizer. Your doctor will demonstrate the proper way to use the nebulizer. Be sure to only use the nebulizer recommended by your doctor.


• If Mucomyst Solution is used with a face mask, a sticky substance may appear on the face. The stickiness can be removed by washing the face with water.


• If you miss a dose of Mucomyst Solution, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Mucomyst Solution.

Important safety information:

• A slightly unpleasant odor may be noticeable while using Mucomyst Solution.


• Mucomyst Solution may change color in the opened bottle. This is harmless.


• If your breathing does not get better or if it gets worse, check with your doctor.


• Lab tests may be performed while you use Mucomyst Solution. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Mucomyst Solution while you are pregnant. It is not known if Mucomyst Solution is found in breast milk. If you are or will be breast-feeding while you use Mucomyst Solution, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Mucomyst Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Cold, clammy skin; drowsiness; fever; inflammation of the mouth or tongue; nausea; runny nose; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); mouth sores; throat and lung irritation.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Mucomyst side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Mucomyst Solution:

Store unopened vials of Mucomyst Solution at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Mucomyst Solution may be contaminated once opened. Store opened vials of undiluted medicine in the refrigerator between 36 and 46 degrees F (2 and 8 degrees C) for up to 4 days. Do not store in the bathroom. Keep Mucomyst Solution out of the reach of children and away from pets.

General information:

• If you have any questions about Mucomyst Solution, please talk with your doctor, pharmacist, or other health care provider.


• Mucomyst Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Mucomyst Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Mucomyst resources

• Mucomyst Side Effects (in more detail)
• Mucomyst Use in Pregnancy & Breastfeeding
• Mucomyst Drug Interactions
• Mucomyst Support Group
• 1 Review for Mucomyst - Add your own review/rating

Compare Mucomyst with other medications

• Acetaminophen Overdose
• Diagnostic Bronchograms
• Expectoration